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aneuploid yeast

aneuploid yeast

Mar 31, 20261 min read

Yeast cells containing an abnormal number of chromosomes, typically with one or more extra or missing chromosomes.

Related Claims

  • Aneuploidy alters cellular protein composition approximately twofold
  • Quantitative proteomics measures 70-80% of yeast open reading frames
  • Protein levels correlate with chromosomal position in aneuploid strains

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  • Aneuploidy alters cellular protein composition approximately twofold
  • Aneuploidy decreases both organismal and cellular fitness
  • Aneuploidy heightens sensitivity to protein synthesis interference
  • Aneuploidy increases glucose uptake in yeast cells
  • Extra chromosome genes drive aneuploid phenotypes through imbalanced protein composition
  • Growth medium conditions affect aneuploid strain proteome composition
  • Protein levels correlate with chromosomal position in aneuploid strains
  • Protein stoichiometry tracks gene dosage in aneuploid cells with high fidelity
  • Proteome consequences of aneuploidy
  • Quantitative proteomics measures 70-80% of yeast open reading frames
  • copy number
  • gene dosage
  • phenotype

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