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oncogenic

oncogenic

Mar 31, 20261 min read

Capable of inducing or promoting the transformation of cells into a malignant cancerous state.

Related Claims

  • Aneuploidy exhibits dual roles as oncogenic and tumor-suppressive
  • Subclonal driver events determine therapy response and tumor evolution

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Backlinks

  • Aneuploidy exhibits dual roles as oncogenic and tumor-suppressive
  • Aneuploidy increases spontaneous tumor formation in aged animals
  • Aneuploidy's dual role in tumorigenesis
  • Aneuploidy, fitness costs, and immune evasion
  • Chromosomal instability generates immunogenic heterogeneity requiring active immune evasion
  • Different aneuploid cells share common fitness-related traits
  • Extra centrosomes correlate with chromosomal instability in tumors
  • Increased aneuploidy inhibits chemically and genetically induced tumorigenesis
  • Primary glioblastomas contain inherent variability in oncogenic signaling expression
  • Subclonal Dynamics in Cancer Evolution
  • Subclonal driver events determine therapy response and tumor evolution
  • aneuploid
  • chromosomal instability
  • models
  • p53 loss is common but not enriched in chromosomally unstable tumors

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