centrosomes

Cellular organelles that serve as the main microtubule-organizing centers (MTOCs) in animal cells, nucleating and organizing microtubules that form the mitotic spindle.

Related Claims

• Extra centrosomes promote chromosome missegregation during bipolar division
• Multipolar spindle intermediate allows merotelic attachment accumulation
• Multipolar divisions are rare and typically produce inviable progeny
• Extra centrosomes correlate with chromosomal instability in tumors