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centrosome clustering

centrosome clustering

Mar 31, 20261 min read

The process by which extra centrosomes in a cell aggregate together to form fewer functional spindle poles prior to or during cell division.

Related Claims

  • Multipolar spindle intermediate allows merotelic attachment accumulation

Graph View

Backlinks

  • Elevated merotely generates CIN in stable near-diploid cells
  • Extra centrosomes promote chromosome missegregation during bipolar division
  • Merotelic attachments mechanistically link centrosome amplification to chromosomal instability
  • Merotely causes chromosome missegregation in unstable cells
  • Mitotic spindle architecture and chromosome segregation
  • Multipolar spindle intermediate allows merotelic attachment accumulation

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