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CENP E

CENP-E

Mar 31, 20261 min read

  • centromere-protein-E

A mitosis-specific motor protein that is linked to the centromere and functions to organize kinetochore-microtubule attachments and chromosome segregation during cell division.

Related Claims

  • CENP-E reduction generates aneuploidy and chromosomal instability

Graph View

Backlinks

  • CENP-E motor protein function
  • CENP-E reduction generates aneuploidy and chromosomal instability
  • CIN causality toward aneuploidy was previously unanswered
  • Elevated merotely generates CIN in stable near-diploid cells

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